Fruit Pectin for Prostate Cancer

Cancer Growth is Driven by 14 Hallmarks

What steps can you take to stop prostate cancer progression?

The older a man is, the greater the chance he has of getting prostate cancer. Some men are at increased risk for prostate cancer.

Pharmaceutical grade and researched supplements containing fruit pectin have been shown to have anti-metastatic properties in prostate cancer.

Modified citrus pectin (MCP) is obtained from the peel and pulp of citrus fruits and modified to affect numerous rate-limiting steps to slow or stop cancer metastasis. These particular and specific pectins have “anti-adhesive” properties as well as the potential for increasing the death of cells. Modified citrus pectin acts on a carbohydrate binding protein named Galectin-3. During digestion, these pectins bind to and block the activity of the Galectin-3 which has a role in tumor progression.

Galectin-3 is one of the most studied binding proteins and increasing research is demonstrating that Galectin-3 is directly and indirectly connected to cancer cell activity that can contribute to cancer growth, cancer blood cell formation, increased cancer progression and metastasis.

As with any cancer preventive supplement, fruit pectin containing supplements need to be carefully prescribed by a functional medicine or functional oncology professional. Supplements containing modified fruit pectin must come from a reputable and research-based company.

If you have cancer, you want to try anything if you think it may help treat your cancer. Do not try to treat yourself with supplements that are advertised to prevent or treat cancer, it is important to consult with a reputable and educated provider first before taking an alternative or complementary therapy.

You could harm your health if you stop your prescribed prostate cancer treatment plan for an unproven treatment. Hyperion Functional Medicine uses only research-based supplements in functional oncology to support cancer treatment plans.

Contact Hyperion Functional Medicine to learn more.

Supporting Research:
Califice S, Castronovo V, Bracke M, van den Brûle F. Dual activities of galectin-3 in human prostate cancer: tumor suppression of nuclear galectin-3 vs tumor promotion of cytoplasmic galectin-3. Oncogene. 2004 Sep 30;23(45):7527-36. doi: 10.1038/sj.onc.1207997. PMID: 15326483.

Eliaz, I., McKee, D. L. (2014, September). Galectin-3 as an Oncological Biomarker: A review of its possible role in cancer treatment response and disease progression. Natural Medicine Journal (Vol. 6 Issue 9)

Emran TB, Islam F, Mitra S, Paul S, Nath N, Khan Z, Das R, Chandran D, Sharma R, Lima CMG, Awadh AAA, Almazni IA, Alhasaniah AH, Guiné RPF. Pectin: A Bioactive Food Polysaccharide with Cancer Preventive Potential. Molecules. 2022 Oct 31;27(21):7405. doi: 10.3390/molecules27217405. PMID: 36364232; PMCID: PMC9657392.

Funasaka, T., Raz, A., & Nangia-Makker, P. (2014). Galectin-3 in angiogenesis and metastasis. Glycobiology, 24(10), 886-891

Glinsky VV, Raz A. Modified citrus pectin anti-metastatic properties: one bullet, multiple targets. Carbohydr Res. 2009 Sep 28;344(14):1788-91. doi: 10.1016/j.carres.2008.08.038. Epub 2008 Sep 26. PMID: 19061992; PMCID: PMC2782490.

Hara A, Niwa M, Noguchi K, Kanayama T, Niwa A, Matsuo M, Hatano Y, Tomita H. Galectin-3 as a Next-Generation Biomarker for Detecting Early Stage of Various Diseases. Biomolecules. 2020 Mar 3;10(3):389. doi: 10.3390/biom10030389. PMID: 32138174; PMCID: PMC7175224.

Kim SJ, Chun KH. Non-classical role of Galectin-3 in cancer progression: translocation to nucleus by carbohydrate-recognition independent manner. BMB Rep. 2020 Apr;53(4):173-180. doi: 10.5483/BMBRep.2020.53.4.020. PMID: 32172730; PMCID: PMC7196190.

Yan J., Katz A. PectaSol-C modified citrus pectin induces apoptosis and inhibition of proliferation in human and mouse androgen-dependent and-independent prostate cancer cells. Integr. Cancer Ther. 2010;9:197–203. doi: 10.1177/1534735410369672.